CAS 80863-62-3 Alitame
Synonyms: (3s)-3-amino-4-oxo-4-[[(2r)-1-oxo-1-[(2,2,4,4-tetramethylthietan-3-yl)amino]propan-2-yl]amino]butanoic acid;(S)-3-amino-4-(((R)-1-amino-1-oxopropan-2-yl)(2,2,4,4-tetramethylthietan-3-yl)amino)-4-oxobutanoic acid;(S)-3-Amino-4-oxo-4-(((R)-1-oxo-1-((2,2,4,4-tetramethylthietan-3-yl)amino)propan-2-yl)amino)bu;(S)-3-((R)-1-(2,2,4,4-TETRAMETHYLTHIETAN-3-YLCARBAMOYL)ETHYLCARBAMOYL)-3-AMINOPROPANOIC ACID;Alitame;l-alpha-aspartyl-n-(2,2,4,4-tetramethyl-3-thietanyl)-d-alaninamide;l-α-aspartyl-N-(2,2,4,4-tetramethyl-3-thietanyl)-D-alaninamide;CP 54802
CAS: 80863-62-3
MF
Alitame Chemical Properties:
Melting point: 136-147°
alpha: D25 +40 to +50° (c = 1 in water)
Boiling point: 608.5±55.0 °C(Predicted)
Density: 1.25±0.1 g/cm3(Predicted)
pka: 3.71±0.10(Predicted)
HS Code: 29400090
Chemical Properties: White Solid
Chemical Properties: Alitame is a white nonhygroscopic crystalline powder; odorless or having a slight characteristic odor.
Uses: Alitame [L-a-aspartyl-N-(2,2,4,4-tetramethyl-3-thietanyl)-D-alaninamide] is a sweetener based on an amino acid. It is a very intense sweetener, possessing a sweetening power of about 2000 times that of sucrose. It also exhibits a clean sweet taste similar to sucrose. Although it is metabolized, so little is needed that its caloric contribution is insignificant. Alitame is prepared from the amino acids, L-aspartic acid, D-alamine, and a novel amine.
Uses: Non-nutritive sweetener.
Uses: Alitame is a dipeptide amide derivative of aspartic acid used as an artificial sweetener. Alitame is about ten times sweeter than Aspartame (A790015) with a half life about twice as long.
Pharmaceutical Applications: Alitame is an intense sweetening agent developed in the early 1980s and is approximately 2000 times sweeter than sucrose. It has an insignificant energy contribution of 6 kJ (1.4 kcal) per gram of alitame.
Alitame is currently primarily used in a wide range of foods and beverages at a maximum level of 40–300 mg/kg.
Storage: Alitame is stable in dry, room temperature conditions but undergoes degradation at elevated temperatures or when in solution at low pH. Alitame can degrade in a one-stage process to aspartic acid and alanine amide (under harsh conditions) or in a slow two-stage process by first degrading to its β-aspartic isomer and then to aspartic acid and alanine amide. At pH 5–8, alitame solutions at 238℃ have a half-life of approximately 4 years. At pH 2 and 238℃ the half-life is 1 year.
Alitame should be stored in a well-closed container in a cool, dry place.
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