
CAS 9003-11-6 188 Polyethylene-polypropylene glycol
Product Name: 188 Polyethylene-polypropylene glycol
Synonyms: BLOCK COPOLYMER OF POLYETHYLENE AND POLYPROPYLENE GLYCOL;Poloxamer;POLOXAMER 184 NF;Polypropylene-polyethylene glycol: (Pluronic L-81);PEG-PPG-PEG;Pluronic(R) L64, Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol), Poly(propylene glycol)-block-poly(ethylene glycol)-block-poly(propylene glycol);Synperonic(R) PE/L64;POLOXAMER 181 NF
CAS: CAS 9003-11-6
MF: C5H10O2
MW: 102.1317
EINECS: 618-355-0
Product Categories: Biological DetergentsSerum-free Media;Companion Products and Reagents;Cell Culture
Product Name: 188 Polyethylene-polypropylene glycol
Synonyms: BLOCK COPOLYMER OF POLYETHYLENE AND POLYPROPYLENE GLYCOL;Poloxamer;POLOXAMER 184 NF;Polypropylene-polyethylene glycol: (Pluronic L-81);PEG-PPG-PEG;Pluronic(R) L64, Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol), Poly(propylene glycol)-block-poly(ethylene glycol)-block-poly(propylene glycol);Synperonic(R) PE/L64;POLOXAMER 181 NF
CAS: CAS 9003-11-6
MF: C5H10O2
MW: 102.1317
EINECS: 618-355-0
Product Categories: Biological DetergentsSerum-free Media;Companion Products and Reagents;Cell Culture;Insect Platform;Reagents and Supplements;Polymers;surfactant, Dow;Surfactant;Block Copolymers;Detergents and Surfactants;PEG-PPG Copolymers;Biocompatible/Biodegradable Materials;Ethers;Materials Science;PEG-PPG CopolymersHydrophobic Polymers;Propylene Glycol;Surfactants Classified by HLB Numbers;Biomaterials;Contact Printing;Materials Science;Micro/NanoElectronics;Nonionic;Polymer Additives;Polymer Science;Self Assembly &;Self-Assembly Materials;Surfactants
188 Polyethylene-polypropylene glycol Chemical Properties:
Melting point: 57-61 °C
Boiling point: >200 °C(lit.)
Density: 1.095 g/mL at 25 °C
vapor density: >1 (vs air)
vapor pressure: <0.3 mm Hg ( 20 °C)
refractive index: n20/D 1.466
Fp: >230 °F
Storage temp.: 2-8°C
solubility: H2O: at <70 °Csoluble
Form: solution
Color: APHA: ≤120, 50/50 in CH3OH
PH: 5.0-7.5 (100g/L in H2O)
PH Range: 5.0 - 7.5
Water Solubility: Miscible with water.
λmax: λ: 260 nm Amax: ≤0.3
λ: 280 nm Amax: ≤0..2
HS Code: 39059100
Uses: Polyethylene-polypropylene glycol is a liquid surfactant polymer.
Uses: Hard and soft surface cleaners, defoamers in coatings and water treatment. Lubricant in metal working, anti-foaming aid and extender for linear and cross-linked polyesters and polyurethanes.
Uses: pyrethroid-based pesticide for use in mosquito control
Pharmaceutical Applications: Polyethylene-polypropylene glycol is nonionic polyoxyethylene–polyoxypropylene copolymers used primarily in pharmaceutical formulations as emulsifying or solubilizing agents.The polyoxyethylene segment is hydrophilic while the polyoxypropylene segment is hydrophobic. All of the Polyethylene-polypropylene glycol is chemically similar in composition, differing only in the relative amounts of propylene and ethylene oxides added during manufacture. Their physical and surface-active properties vary over a wide range and a number of different types are commercially available;
Polyethylene-polypropylene glycol is used as emulsifying agents in intravenous fat emulsions, and as solubilizing and stabilizing agents to maintain the clarity of elixirs and syrups. Polyethylene-polypropylene glycol may also be used as wetting agents; in ointments, suppository bases, and gels; and as tablet binders and coatings.
Poloxamer 188 has also been used as an emulsifying agent for fluorocarbons used as artificial blood substitutes, and in the preparation of solid-dispersion systems. More recently,Polyethylene-polypropylene glycol has found use in drug-delivery systems.
Therapeutically, poloxamer 188 is administered orally as a wetting agent and stool lubricant in the treatment of constipation; it is usually used in combination with a laxative such as danthron. Polyethylene-polypropylene glycol may also be used therapeutically as wetting agents in eye-drop formulations, in the treatment of kidney stones, and as skin-wound cleansers.
Poloxamer 338 and 407 are used in solutions for contact lens care.
Storage: Polyethylene-polypropylene glycol is stable materials. Aqueous solutions are stable in the presence of acids, alkalis, and metal ions. However, aqueous solutions support mold growth.
The bulk material should be stored in a well-closed container in a cool, dry place.
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